Clinical Trials & Research
Montefiore is the University Hospital for Albert Einstein College of Medicine. This unique partnership brings together expertise across disciplines and yields an extensive portfolio of biomedical research, with an emphasis on translating basic science in the lab to pioneering treatments and therapies. Montefiore physicians are discovering novel solutions that advance the future of healthcare and treatments:
$3.5 Million Grant Expands Access to Innovative Care for Hepatitis C
As one of six recipients of the Health Care Innovation Award from the Center for Medicare & Medicaid Services, Montefiore is working to increase access to effective hepatitis C care for patients. Through the grant, Montefiore Einstein researcher Alain Litwin, MD will continue to develop and study models of hepatitis C virus care.
The $3.5 million grant will allow us to identify, diagnose and treat people with hepatitis C (HCV) throughout the Bronx. An estimated 146,500 New Yorkers have chronic hepatitis C, though about half do not know that they are infected. The award, called Project INSPIRE NYC, will increase the number of patients starting hepatitis C therapy, strengthen management of behavioral health problems, and reduce hospitalizations and emergency department visits.
Over three years, we will use an integrated model of care for Medicare and Medicaid patients who are at risk for hepatitis C. Primary care champions will work closely with care coordinators and specialists to increase access to effective hepatitis C care for patients. HCV care coordinators will provide care coordination, navigation, health promotion, and medication adherence to offer each enrollee a patient-centered medical home. Also available to patients will be a peer educator, a person who was cured of hepatitis C, who can share his or her experiences and help patients navigate through the process.
The project will be supported by a telemedicine system linking a hepatologist, infectious diseases specialist, and mental health provider with the primary care provider. Its goal is to further educate the physician and increase the capacity of patients served.
“This innovative model of care builds on our strengths and commitment to our community and will avert deadly consequences of chronic hepatitis C for many people living in the Bronx,” says Dr. Litwin. “We will be able to make a significant impact in combating hepatitis C by innovating the way we deliver health care, on par with other innovations. That’s the whole point of Project INSPIRE NYC.”
Alain Litwin, MD, is Professor of Medicine at Montefiore Medical Center and Albert Einstein College of Medicine.
Relief for Adults with Aspirin-Sensitive Asthma
The asthma rate among adults in the Bronx is more than twice the national average. In addition, about 10 percent of the adult asthmatics and 40 percent of patients with asthma and nasal polyps, are also dealing with Aspirin-Exacerbated Respiratory Disease or AERD—sensitivity to aspirin and other non-steroidal anti-inflammatory drugs, including ibuprofen and naproxen.
To diagnose the AERD, patients take part in a low-dose aspirin challenge. Currently considered the gold-standard diagnostic test, the aspirin challenge can induce asthma attacks in 40 to 85% of the people who undergo it.
A new study by Elina Jerschow, MD, Director of the Montefiore Drug Desensitization Program, aims to develop a safer, quicker, more cost-efficient method of identifying aspirin-sensitive asthma and explain the underlying causes of AERD, which has created a barrier in developing effective treatments. Learn more.
Clinical Trials Database
Patients at Montefiore have access to an extensive array of clinical research studies and clinical trials designed to determine the safety and efficacy of new treatments, while helping eligible patients gain access to innovative treatments. Montefiore physicians BS researchers are involved in more than 400 clinical trials and research studies to evaluate the effectiveness and safety of innovative treatments and diagnostics.
Use our comprehensive search tool to find a clinical trial that that meets your needs.