Clinical Trials & Research
Montefiore is the University Hospital for Albert Einstein College of Medicine. This unique partnership brings together expertise across disciplines and yields an extensive portfolio of biomedical research, with an emphasis on translating basic science in the lab to pioneering treatments and therapies. Montefiore physicians are discovering novel solutions that advance the future of healthcare and treatments:
While cancer mortality rates are declining, minority and underserved populations have yet to show improvement. Through an NIH grant, Montefiore-Einstein researchers Joseph Sparano, MD, Mark Einstein, MD, MS and Bruce Rapkin, PhD are working to change this.
As one of 12 sites to participate in the NCI Community Oncology Research Program (NCORP), Montefiore will use the $3.4 million grant to reduce healthcare disparities in cancer care. The program will be conducted at Montefiore Einstein Center for Cancer Care, our premier cancer center that provides patient-centered care for prevention, diagnosis and treatment of cancer. The NCORP research will be directed by three investigators: Dr. Sparano will lead efforts in cancer therapeutics; Dr. Einstein will oversee cancer prevention; and Dr. Rapkin will focus on cancer control and delivery.
“Albert Einstein Cancer Center has played a key leadership role in therapeutic cancer trials and has received funding from NCI for nearly four decades to support its role as a main member institution of the Eastern Cooperative Oncology Group,” says Dr. Sparano. “The NCORP funding will support expanding activities in the areas of cancer prevention, cancer control and cancer care delivery research.”
In addition to leading cancer clinical research at Montefiore, Dr. Sparano has focused on enhancing the access of minority populations to cancer clinical trials as an essential component of contemporary cancer care. “Cancer mortality rates are declining rapidly as a result of improved treatment, screening and prevention, but improvements have lagged in minority populations,” adds Dr. Sparano. “Clinical trials have provided a foundation for much of this improvement. The NCORP mechanism will allow us to integrate new approaches that may address this disparity.”
Joseph Sparano, MD, is Professor of Medicine and of Obstetrics and Gynecology and Women's Health, and Associate Director of Clinical Research, Einstein; and Vice Chairman of Medical Oncology, Center for Cancer Care.
Mark Einstein, MD, MS, is Professor and Director of Oncology Research in the Department of Obstetrics and Gynecology and Women's Health, Einstein; and Vice Chair of Research for Obstetrics and Gynecology and Women's Health, Center for Cancer Care.
Bruce Rapkin, PhD, is Professor of Epidemiology and Population Health at Einstein and Center for Cancer Care.
Relief for Adults with Aspirin-Sensitive Asthma
The asthma rate among adults in the Bronx is more than twice the national average. In addition, about 10 percent of the adult asthmatics and 40 percent of patients with asthma and nasal polyps, are also dealing with Aspirin-Exacerbated Respiratory Disease or AERD—sensitivity to aspirin and other non-steroidal anti-inflammatory drugs, including ibuprofen and naproxen.
To diagnose the AERD, patients take part in a low-dose aspirin challenge. Currently considered the gold-standard diagnostic test, the aspirin challenge can induce asthma attacks in 40 to 85% of the people who undergo it.
A new study by Elina Jerschow, MD, Director of the Montefiore Drug Desensitization Program, aims to develop a safer, quicker, more cost-efficient method of identifying aspirin-sensitive asthma and explain the underlying causes of AERD, which has created a barrier in developing effective treatments. Learn more.
Clinical Trials Database
Patients at Montefiore have access to an extensive array of clinical research studies and clinical trials designed to determine the safety and efficacy of new treatments, while helping eligible patients gain access to innovative treatments. Montefiore physicians BS researchers are involved in more than 400 clinical trials and research studies to evaluate the effectiveness and safety of innovative treatments and diagnostics.
Use our comprehensive search tool to find a clinical trial that that meets your needs.