Clinical Trials & Research
Spotlight on Research
Montefiore is the University Hospital for Albert Einstein College of Medicine. This unique partnership brings together expertise across disciplines and yields an extensive portfolio of biomedical research, with an emphasis on translating basic science in the lab to pioneering treatments and therapies. Montefiore physicians are discovering novel solutions that advance the future of healthcare and treatments for the following:
HIV/AIDS in Women
Montefiore Medical Center and Albert Einstein College of Medicine received a $16 million grant from the National Institutes of Health (NIH) to investigate the impact of HIV and AIDS on women.
Kathryn M. Anastos, MD, has served as one of the study's six principal investigators since the Women's Interagency HIV Study was established in 1993. Dr. Anastos has partnered with researchers to determine the clinical care HIV-positive women should receive for human papillomavirus (HPV), implement an electronic records system to collect and analyze data on patients receiving antiretroviral therapy in central Africa, and develop clinical services and build research capacity in Rwanda.
Facing months and years on an organ donor list may become a thing of the past, if current stem cell research at Montefiore—in partnership with investigators at the Marion Bessin Liver Research Center and the Ruth L. and David S. Gottesman Institute for Stem Cell Biology and Regenerative Medicine at Albert Einstein College of Medicine—provides a viable alternative to transplantation.
Sanjeev Gupta, MD, a world leader in liver-directed cell and gene therapy and stem cell biology, is currently exploring a promising approach that combines stem cells with gene therapy. Dr. Gupta is a pioneer in the development of cell therapy – treating disease by introducing healthy cells into the body. He has discovered various mechanisms for coaxing transplanted cells to attach to host tissue and multiply, paving the way for treating health problems such as liver failure, hepatitis, high cholesterol and hemophilia.
In 2012, two research teams at Montefiore and Einstein were awarded grants from the National Cancer Institute (NCI) as part of their "Provocative Questions" program.
The first grant — awarded to Steven K. Libutti, MD, Director, Montefiore Einstein Center for Cancer Care, and Richard N. Kitsis, MD, will investigate why certain mutations promote cancer in some tissues of the body but not in others. The researchers will try to identify the factors responsible for this phenomenon, which they call "tissue-selective tumorigenesis."
The innovative effort is designed to ignite investigations into 24 promising but neglected or unexplored areas of research. Answering the questions would dramatically enhance ongoing efforts to prevent, treat and cure the disease. The grants—two of only 57 given nationwide and only five in New York City, and totaling more than $3 million over the next five years—are aimed at determining why cancer arises in certain tissues and how the disease spreads.
Waging a Battle Against Cervical Cancer
Mark Einstein, MD, director of clinical research for women's health and gynecologic oncology at Montefiore, is at the center of great progress currently being made against cervical cancer. Dr. Einstein's research—pinpointing the specific cells that cause cervical cancer when infected by HPV—could probably be quickly translated into new tests to screen for and treat cervical cancer. Learn more.
Clinical Trials Database
Patients at Montefiore have access to an extensive array of clinical research studies and clinical trials designed to determine the safety and efficacy of new treatments, while helping eligible patients gain access to innovative treatments. Montefiore physicians BS researchers are involved in more than 400 clinical trials and research studies to evaluate the effectiveness and safety of innovative treatments and diagnostics.
Use our comprehensive search tool to find a clinical trial that that meets your needs.