Research Training
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Blood (Hematology)

Research Training

Hematology Oncology fellows at Montefiore Medical Center and the Albert Einstein College of Medicine receive an exceptional education in the methodology, execution, and interpretation of studies through rigorous clinical and basic research training. Since its establishment in 1959, our fellowship program has distinguished itself with greater emphasis on active clinical research than most other institutions. Under the supervision and mentorship of a faculty of nearly 30 experts, this intense investigative foundation prepares fellows to participate in and lead effective research teams and become outstanding academic and clinical practice leaders.

Clinical and Basic Research Opportunities

Fellows may choose from a broad spectrum of cutting-edge clinical and basic hematology and oncology research endeavors. Some areas of focus include: colon cancer (basic oncology to new prevention strategies and therapies), breast and lung cancer, phase 1 studies on malignancies, thrombosis, hemoglobinopathy, stem cell biology and molecular biology, TTP, von Willebrand's disease, red cell membrane defects, malaria, cellular cation transportation, lymphocyte biology, and MDS.

Our Thrombosis and Sickle Cell Programs and Cancer Center have greatly enhanced fellows' research projects for the past 30 years, resulting in a myriad of new developments in diagnostic techniques, medications, procedures, and healthcare discoveries. The Thrombosis Center houses one of the largest thrombosis prevention treatment programs in the nation, the Sickle Cell Program is one of only 10 centers across the country supported by the NIH, and the Cancer Center, which receives NCI funding, is a nationally-recognized resource site for various pilot studies that advance to cooperative group clinical trials. More than 400 patients are accrued each year to participate in clinical trials.

Additionally, our Cancer Center programs span a wide range of basic and translational research fields. Programs encompass: the immune system, viruses in cancer, tumor cell membranes at the biochemical, molecular, and functional levels, cell growth at the levels of membrane receptors and downstream signaling molecules and transcription. We also have translational research programs in anticancer drug development that employ structural biology technologies to target novel protein sites.

Each fellow completes two projects during his or her training period:

  • Clinical Seminar:  All fellows are required to present a seminar between September-June of their final year based on a scholarly literature review of a specific topic of their choosing that will be presented to Hematology Oncology Grand Rounds. Faculty members are available to provide direction.
  • Clinical or Laboratory Research Project:  All fellows are strongly encouraged to engage in at least one clinical or laboratory research project that will ideally culminate into an oral presentation first delivered to faculty and peers, then at a national or regional meeting as a poster or oral presentation.

Our faculty is available to assist fellows in customizing a training program that meets their individual goals. We are please to report that the fellows' diligent research have produced multiple young investigator awards over the past several years.

Lectures and Conferences

The research experience is augmented by lectures and core conferences, including weekly multidisciplinary tumor board meetings, which enable fellows to participate in new patient cases, review pathology and radiographic studies, and discuss the management for each. Attendance is mandatory at our Oncology Core Conferences for fellows on an oncology rotation and at our Hematology Core Conferences for those on a hematology rotation. Likewise, attendance at the following core and clinical case conferences is required for fellows conducting specific rotations:

Core Conferences (and their frequency)

  • Grand Rounds
    • Hematology Grand Rounds (weekly)
    • Oncology Grand Rounds (weekly)
  • Journal Clubs
    • Hematology Journal Club (every 2 weeks)
    • Oncology Journal Club (every month)
  • Oncology Clinical Research Conference (monthly)
    Hematology Thrombosis Seminar (every two weeks)
  • Oncology Basic Science Conference (monthly directed by Dr. Amit Verma)
  • Joint Hematology/Oncology Conference (6 times year)

Other Clinical Case Conferences

  • Oncology
  • Liver — GI Tumor Board (every week)
  • Thoracic oncology Tumor board (weekly)
  • Head & Neck Cancer Tumor Board (weekly)
  • Breast Tumor board (weekly)
  • Leukemia-Lymphoma Conference (every 2 weeks)
  • New case conference (weekly)
  • Hematology
  • Faculty Interesting Case Conference (every 2 weeks)
  • Fellow Interesting Case Conference (every 2 weeks)
  • Coagulation Case Conference (every 2 weeks)
  • Red Cell Case Conference (every 2 weeks)
  • Transfusion Medicine Conference (every 2 weeks)
  • Hematopathology Conference (every two weeks)
  • Morphology Conference (weekly)

We also have a formal curriculum addressing ethical, medico-legal, and socioeconomic issues integrated into the program. The principal components include: core lectures, psychosocial oncology rounds, pain management and palliative care lectures, and routine discussions with social workers, and instruction on blood product approval protocols.