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Montefiore in the News

December 13, 2019

Foiling Epilepsy in a Brain at Risk
Neurologist, Dr. Aristea Galanopoulou, and other researchers in a global consortium, are studying traumatic brain injuries to find biomarkers that may signal the future development of epilepsy in people with brain-injuries.

Jennifer Couzin-Frankel | Science  13 Dec 2019: Vol. 366, Issue 6471, pp. 1304

Summary

About 30% of people who suffer a severe traumatic brain injury (TBI)—and a smaller percentage of people with a milder one—later develop epilepsy. Three years ago, a $21 million project spanning five countries took the first steps toward epilepsy prevention for brain-injured patients: searching for biomarkers that presage epilepsy and, in animals, drugs that prevent it. Physicians treating TBI could follow the lead of the first epilepsy prevention trial, which is testing the epilepsy drug vigabatrin in babies with a rare genetic syndrome called tuberous sclerosis complex that comes with a very high risk of the seizure disorder.