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Title Disease/Condition Principal Investigator
A Combination Study of PF-04449913 (Glasdegib) and Azacitidine In Untreated MDS, AML and CMML Patients (BRIGHT 1012) Myelodysplastic Syndrome (MDS),Hematologic Diseases,Oncology (Medical/Hematologic),Leukemia,Neoplasms  Amit Verma, MD 
A Feasibility and Biomarker Study to Evaluate Necitumumab in the Neoadjuvant Setting With Gemcitabine and Cisplatin in Surgically Resectable Squamous Lung Cancer Lung Cancer,Oncology (Medical/Hematologic),Lung Diseases,Neoplasms  Balazs Halmos, MD 
A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) for Transplantation in Pediatric and Adult Patients With Hematologic Malignancies and Other Indications Blood Disorders and Diseases,Hematologic Diseases,Oncology (Medical/Hematologic),Pediatric Hematology/Oncology,Leukemia,Non-Hodgkins Lymphoma,Lymphoma,Neoplasms,Anemia,Lymphoproliferative Disorders,Immune System Diseases  David Loeb, MD 
A Multicenter, Open-Label, Phase 1B/2 Study to Evaluate Safety and Efficacy of Avelumab (MSB0010718C) IN COMBINATION WITH Chemotherapy With Or Without Other Anti-Cancer Immunotherapies as First-Line Treatment In Patients With Advanced Malignancies Lung Cancer,Oncology (Medical/Hematologic),Lung Diseases,Carcinoma,Neoplasms  Balazs Halmos, MD 
A Multicenter, Open-label, Randomized, Phase 3 Trial to Compare the Efficacy and Safety of Lenvatinib in Combination With Everolimus or Pembrolizumab Versus Sunitinib Alone in First-Line Treatment of Subjects With Advanced Renal Cell Carcinoma (CLEAR) Kidney Diseases (incl Chronic Kidney Disease),Kidney Cancer,Oncology (Medical/Hematologic),Urologic Oncology (Med Onc),Urologic Diseases,Carcinoma,Urogenital Neoplasms  Benjamin Gartrell, MD 
A Phase 1 Dose Escalation and Cohort Expansion Study of TSR-022, an Anti-TIM-3 Monoclonal Antibody, in Patients With Advanced Solid Tumors (AMBER) Colon, Colorectal and Rectal Cancer,Lung Cancer,Solid Tumor,Metastatic Cancer,Oncology (Medical/Hematologic),Neoplasms  Sanjay Goel, MD 
A Phase 1 Dose-ranging Study to Investigate the Safety, Tolerability, and Pharmacokinetics of MRG-106 Following Local Intratumoral, Subcutaneous, and Intravenous Administration in Subjects With Various Lymphomas and Leukemias Oncology (Medical/Hematologic),Leukemia,Non-Hodgkins Lymphoma,Lymphoma,Lymphatic and Spleen Diseases,Neoplasms,Lymphoproliferative Disorders,Immune System Diseases  Noah Kornblum, MD 
A Phase 1, Open-Label, Non-Randomized, Safety, Tolerability and Pharmacokinetic Study of TAS3681 in Patients With Metastatic Castration Resistant Prostate Cancer Prostate Cancer,Oncology (Medical/Hematologic),Urogenital Neoplasms  Benjamin Gartrell, MD 
A Phase 1-2 Multi-Center Study Evaluating KTE-C19 in Subjects With Refractory Aggressive Non-Hodgkin Lymphoma (ZUMA-1) (ZUMA-1) Blood and Bone Marrow Cancer  Ira Braunschweig, MD 
A Phase 1/1b Study of MGCD516 in Patients With Advanced Solid Tumor Malignancies Head and Neck Cancer,Lung Cancer,Prostate Cancer,Solid Tumor,Kidney Cancer,Carcinoma,Neoplasms  Sanjay Goel, MD 
A Phase 1b Dose-Escalation Study of Cabozantinib (XL184) Administered Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors Colon, Colorectal and Rectal Cancer,Gastrointestinal Cancer,Head and Neck Cancer,Lung Cancer,Prostate Cancer,Solid Tumor,Thyroid Cancer,Kidney Cancer,Metastatic Cancer,Oncology (Medical/Hematologic),Carcinoma  Sanjay Goel, MD 
A Phase 1b Study to Assess the Safety, Tolerability, and Clinical Activity of BGB-290 in Combination with Temozolomide (TMZ) in Subjects with Locally Advanced or Metastatic Solid Tumors Breast Cancer,Gastrointestinal Cancer,Lung Cancer,Prostate Cancer,Solid Tumor,Oncology (Medical/Hematologic),Cancer,Neoplasms  Sanjay Goel, MD 
A Phase 1b/2, Open-Label, Dose Escalation Study to Evaluate the Safety, Pharmacokinetics, and Efficacy of SM88 in Patients With Prostate Cancer Prostate Cancer,Oncology (Medical/Hematologic),Urologic Oncology (Med Onc),Neoplasms,Urogenital Neoplasms  Benjamin Gartrell, MD 
A Phase 1b/2a, Multi-Center Open-Label Study to Evaluate the Safety and Efficacy of Combination Treatment With MEDI0457 (INO-3112) and Durvalumab (MEDI4736) in Patients With Recurrent/Metastatic HPV Associated Head and Neck Squamous Cancer Head and Neck Cancer,Medical and Hematologic Oncology,Oncology (Medical/Hematologic),Human Papilloma Virus (HPV),Neoplasms  Balazs Halmos, MD 
A Phase 2 Open-Label, Randomized Study of PARP Inhibition (Olaparib) Either Alone or in Combination With Anti-PD-L1 Therapy (Atezolizumab; MPDL3280A) in Homologous DNA Repair (HDR) Deficient, Locally Advanced or Metastatic Non-HER2-Positive Breast Cancer Breast Cancer,Oncology (Medical/Hematologic),Neoplasms  Jesus Anampa Mesias, MD 
A Phase 2 Study of Poziotinib in Patients With Non-Small Cell Lung Cancer (NSCLC), Locally Advanced or Metastatic, With EGFR or HER2 Exon 20 Insertion Mutation (ZENITH20) Lung Cancer,Metastatic Cancer,Genetic Disorders,Oncology (Medical/Hematologic)  Haiying Cheng, MD 
A Phase 2 Study of the Safety, Tolerability, and Efficacy of Parsaclisib in Combination With Ruxolitinib in Subjects With Myelofibrosis Blood and Bone Marrow Cancer,Blood Disorders and Diseases,Hematologic Diseases,Medical and Hematologic Oncology,Oncology (Medical/Hematologic),Cancer,Myelofibrosis  Swati Goel, MD 
A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Assess Safety and Efficacy of Topically-applied AG013 for the Attenuation of Oral Mucositis in Subjects w/Cancers of Head and Neck Receiving Concomitant Chemoradiation Therapy Head and Neck Cancer,Gastroenterology & Liver Diseases,Oral Mucositis  Madhur Garg, MD 
A Phase 3 Randomized Study Comparing Perioperative Nivolumab vs. Observation in Patients With Localized Renal Cell Carcinoma Undergoing Nephrectomy (PROSPER RCC) Kidney Diseases (incl Chronic Kidney Disease),Lung Cancer,Skin Disorders,Kidney Cancer,Oncology (Medical/Hematologic),Urologic Oncology (Med Onc),Urologic Diseases,Lung Diseases,Carcinoma,Neoplasms,Urogenital Neoplasms  Benjamin Gartrell, MD 
A Phase 3 Study of Androgen Annihilation in High-Risk Biochemically Relapsed Prostate Cancer Prostate Cancer,Oncology (Medical/Hematologic),Neoplasms,Urogenital Neoplasms  Benjamin Gartrell, MD 
A Phase 3 Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Subjects With Advanced Urothelial Cancer and Selected FGFR Gene Aberrations Bladder Cancer,Genetic Disorders,Oncology (Medical/Hematologic),Urologic Oncology (Med Onc),Urologic Diseases,Geriatrics,Urogenital Neoplasms  Benjamin Gartrell, MD 
A Phase I-II Study of PTX-200 Plus Sequential Weekly Paclitaxel Followed by Dose-Dense Doxorubicin and Cyclophosphamide in Patients With Metastatic and Locally Advanced Breast Cancer Breast Cancer,Women`s Health,Oncology (Medical/Hematologic),Carcinoma,Neoplasms  Joseph Sparano, MD 
A Phase I/II Dose Escalation and Expansion Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of GSK525762 in Combination With Fulvestrant in Subjects With HR+/HER2- Advanced or Metastatic Breast Cancer Breast Cancer,Skin Disorders,Medical and Hematologic Oncology,Neoplasms  Sun Young Oh, MD 
A Phase I/IIa, Open Label, Dose-escalation Study Investigating the Safety, Tolerability, and Pharmacokinetics of Intravenous Liposomal Vinorelbine Tartrate Injection in Patients With Advanced Malignancy Oncology (Medical/Hematologic),Lymphoma,Neoplasms  Sanjay Goel, MD 
A Phase II Study of MLN0128 (TAK-228) in Rapalog-Resistant Advanced Pancreatic Neuroendocrine Tumors (PNET) Pancreatic Cancer,Solid Tumor,Metastatic Cancer,Oncology (Medical/Hematologic),Carcinoma,Neoplasms  Lakshmi Rajdev, MD 
A Phase II Trial Assessing the Tolerability of Palbociclib in Combination With Letrozole or Fulvestrant in Patients Aged 70 and Older With Estrogen Receptor-Positive, HER2-Negative Metastatic Breast Cancer Breast Cancer,Women`s Health,Oncology (Medical/Hematologic),Neoplasms  Jesus Anampa Mesias, MD 
A Phase II, Randomized, Multi-Center, Double-Blind, Comparative Global Study to Determine Efficacy and Safety of Durvalumab in Combination With Olaparib for First-Line Treatment in Platinum-Ineligible Patients with Unresectable Stage IV Urothelial Cancer Bladder Cancer,Oncology (Medical/Hematologic),Urologic Oncology (Med Onc),Urologic Diseases,Geriatrics,Neoplasms,Urogenital Neoplasms  Benjamin Gartrell, MD 
A Phase III Study for Patients With Newly Diagnosed Acute Promyelocytic Leukemia (APL) Using Arsenic Trioxide and All-Trans Retinoic Acid Pancreatic Cancer,Oncology (Medical/Hematologic),Pediatric Hematology/Oncology,Leukemia,Neoplasms  Lisa Gennarini, MD 
A Pilot Presurgical Trial of Insulin Inhibition by a Ketogenic Diet in Operable Breast Cancer Breast Cancer,Women`s Health,Oncology (Medical/Hematologic),Neoplasms  Eugene Fine, MD 
A Pilot Study to Assess the Role of Cannabis Added to the Supportive Care Regimen During Chemoradiation for Head and Neck Cancer Head and Neck Cancer,Radiation Oncology,Neoplasms  Rafi Kabarriti, MD 
A Randomized Phase II Clinical Trial Assessing the Efficacy and Safety of MK-3475 (Pembrolizumab) in Combination With Carboplatin and Gemcitabine in Patients With Metastatic Triple Negative Breast Cancer Breast Cancer,Women`s Health,Oncology (Medical/Hematologic),Neoplasms  Sun Young Oh, MD 
A Randomized Phase II Study Comparing Single-Agent Olaparib, Single Agent Cediranib, and the Combination of Cediranib/Olaparib in Women With Recurrent, Persistent or Metastatic Endometrial Cancer Obstetrics & Gynecology and Women`s Health,Urologic Oncology (Med Onc),Cancer,Carcinoma,Urogenital Neoplasms  Nicole Nevadunsky, MD 
A Randomized Phase II Study of Nivolumab After Combined Modality Therapy (CMT) in High Risk Anal Cancer Gastrointestinal Cancer,Anal Cancer,Gastroenterology & Liver Diseases,Radiation Oncology,Carcinoma,Neoplasms  Rafi Kabarriti, MD 
A Randomized Phase III Double Blinded Placebo Controlled Trial of Aspirin as Adjuvant Therapy for HER2 Negative Breast Cancer: The ABC Trial Breast Cancer,Women`s Health,Skin Disorders,Medical and Hematologic Oncology,Neoplasms  Della Makower, MD 
A Randomized Phase III Trial Comparing Axillary Lymph Node Dissection to Axillary Radiation in Breast Cancer Patients (cT1-3 N1) Who Have Positive Sentinel Lymph Node Disease After Neoadjuvant Chemotherapy Breast Cancer,Skin Disorders,Radiation Oncology,Neoplasms  Jana Fox, MD 
A Randomized, Crossover Phase 1 Study to Evaluate the Effects of Pevonedistat on the QTc Interval in Patients With Advanced Solid Tumors Solid Tumor,Metastatic Cancer,Oncology (Medical/Hematologic)  Sanjay Goel, MD 
A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of Rovalpituzumab Tesirine as Maintenance Therapy Following First-Line Platinum-Based Chemotherapy in Subjects With Extensive Stage Small Cell Lung Cancer (MERU) Lung Cancer,Oncology (Medical/Hematologic),Lung Diseases,Carcinoma,Neoplasms  Balazs Halmos, MD 
A Randomized, Multicenter, Double Blind, Phase III Study of Adjuvant Nivolumab or Placebo in Subjects With Resected Esophageal, or Gastroesophageal Junction Cancer (CheckMate 577) Gastrointestinal Cancer,Oncology (Medical/Hematologic),Cancer  Lakshmi Rajdev, MD 
A Randomized, Phase II Efficacy Assessment of Multiple MET Kinase Inhibitors (Cabozantinib [NSC #761968], Crizotinib [NSC #749005], Savolitinib [NSC #785348], and Sunitinib [NSC #736511]) in Metastatic Papillary Renal Carcinoma (PAPMET) Kidney Diseases (incl Chronic Kidney Disease),Kidney Cancer,Oncology (Medical/Hematologic),Urologic Oncology (Med Onc),Carcinoma,Urogenital Neoplasms  Benjamin Gartrell, MD 
A Randomized, Phase II Study Comparing Trastuzumab and Vinorelbine in Combination With Avelumab or Avelumab and Utomilumab (41BB/CD137 Agonist), in Patients With HER2-positive Metastatic Breast Cancer Who Have Progressed on Prior Trastuzumab and Pertuzum Breast Cancer,Skin Disorders,Oncology (Medical/Hematologic),Neoplasms  Sun Young Oh, MD 
A Randomized, Phase II/III Study of Pegylated Liposomal Doxorubicin and CTEP-Supplied Atezolizumab Versus Pegylated Liposomal Doxorubicin/Bevacizumab and CTEP-Supplied Atezolizumab Versus Pegylated Liposomal Doxorubicin/Bevacizumab in Platinum Resistant Obstetrics & Gynecology and Women`s Health,Urologic Oncology (Med Onc),Cancer,Carcinoma,Urogenital Neoplasms  Nicole Nevadunsky, MD 
A Randomized, Phase III Trial to Evaluate the Efficacy and Safety of MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer With = 1 CM Residual Invasive Cancer or Positive Lymph Nodes (ypN+) After Neoadjuvant Chemotherapy Breast Cancer,Women`s Health,Oncology (Medical/Hematologic),Carcinoma,Neoplasms  Jesus Anampa Mesias, MD 
A Simple Walking Program to Enhance Concurrent Chemoradiotherapy Delivery Gastrointestinal Cancer,Head and Neck Cancer,Women`s Health,Brain Cancer,Gastroenterology & Liver Diseases,Radiation Oncology,Urologic Oncology (Med Onc),Cancer,Neoplasms,Urogenital Neoplasms  Nitin Ohri, MD 
A Study Evaluating the Pregnancy Outcomes and Safety of Interrupting Endocrine Therapy for Young Women With Endocrine Responsive Breast Cancer Who Desire Pregnancy (POSITIVE) Breast Cancer,Women`s Health,Skin Disorders,Medical and Hematologic Oncology,Neoplasms  Joseph Sparano, MD 
A Study to Evaluate Efficacy and Safety of Multiple Targeted Therapies as Treatments for Participants With Non-Small Cell Lung Cancer (NSCLC) (B-FAST) Lung Cancer,Oncology (Medical/Hematologic),Lung Diseases,Carcinoma,Neoplasms  Haiying Cheng, MD 
A Trial Comparing Cardiovascular Safety of Degarelix Versus Leuprolide in Patients With Advanced Prostate Cancer and Cardiovascular Disease Prostate Cancer,Cardiology,Oncology (Medical/Hematologic),Urologic Oncology (Med Onc),Urogenital Neoplasms  Benjamin Gartrell, MD 
A Trial of Endocrine Response in Women With Invasive Lobular Breast Cancer Breast Cancer,Women`s Health,Oncology (Medical/Hematologic),Neoplasms  Joseph Sparano, MD 
Abiraterone With Discontinuation of Gonadotropin-Releasing Hormone Analogues in Metastatic Prostate Cancer Prostate Cancer,Oncology (Medical/Hematologic),Urologic Diseases,Urogenital Neoplasms  Benjamin Gartrell, MD 
Alternate Approaches for Clinical Stage II or III Estrogen Receptor Positive Breast Cancer Neoadjuvant Treatment (ALTERNATE) in Postmenopausal Women: A Phase III Study Breast Cancer,Women`s Health,Skin Disorders,Medical and Hematologic Oncology,Carcinoma,Neoplasms  Della Makower, MD 
An Observational Study in Differentiated Thyroid Cancer Which is Radioactive Iodine (RAI) Refractory to Assess the Use of Multikinase Inhibitors (RIFTOS MKI) Head and Neck Cancer  Missak Haigentz, MD 
An Open Label, Phase 2 Pharmacokinetic Study of Pre-Surgical Intramuscular and Intraductal Fulvestrant in Women With Invasive Breast Cancer or DCIS Undergoing Mastectomy or Lumpectomy Breast Cancer,Women`s Health,Skin Disorders,Surgery,Family and Social Medicine,Carcinoma,Neoplasms  Sheldon Feldman, MD 
An Open-label, Multicenter Phase 1 Study to Characterize the Safety, Tolerability, Preliminary Antileukemic Activity, Pharmacokinetics, and Maximum Tolerated Dose or Pharmacological Active Dose of BAY2402234 in Patients With Advanced Myeloid Malignancies Myelodysplastic Syndrome (MDS),Leukemia,Cancer,Neoplasms  Amit Verma, MD 
An Open-Label, Randomized Phase 3 Study to Evaluate Enfortumab Vedotin vs Chemotherapy in Subjects With Previously Treated Locally Advanced or Metastatic Urothelial Cancer (EV-301) Bladder Cancer,Metastatic Cancer,Oncology (Medical/Hematologic),Urologic Oncology (Med Onc),Urologic Diseases,Geriatrics,Neoplasms,Urogenital Neoplasms  Benjamin Gartrell, MD 
An Open-Label, Single-Arm, Phase 2 Study of AVB-620 in Women with Primary, Nonrecurrent Breast Cancer Undergoing Surgery Breast Cancer,Women`s Health,Skin Disorders,Surgery,Carcinoma,Neoplasms  Sheldon Feldman, MD 
Apixaban for the Treatment of Venous Thromboembolism in Patients With Cancer: A Prospective Randomized Open Blinded End-Point (Probe) Study Cardiology,Oncology (Medical/Hematologic),Cancer,Embolism or Thrombosis  Henny Billett, MD 
Assessing the Accuracy of Tumor Biopsies After Chemotherapy to Determine if Patients Can Avoid Breast Surgery Breast Cancer,Oncology (Medical/Hematologic),Radiation Oncology,Neoplasms  Joseph Sparano, MD 
Beta Adrenergic Receptor Blockade as a Novel Therapy for Patients With Adenocarcinoma of the Prostate Prostate Cancer,Oncology (Medical/Hematologic),Urologic Oncology (Med Onc),Urologic Diseases,Carcinoma,Neoplasms,Urogenital Neoplasms  Benjamin Gartrell, MD 
Breast Cancer WEight Loss Study (BWEL Study) Breast Cancer,Women`s Health,Skin Disorders,Overweight, Obesity and Weight Loss,Carcinoma,Neoplasms  Della Makower, MD 
Brentuximab Vedotin and Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed Hodgkin Lymphoma Blood and Bone Marrow Cancer,Pediatric Hematology/Oncology,Lymphoma,Lymphatic and Spleen Diseases,Neoplasms,Lymphoproliferative Disorders,Immune System Diseases  Lisa Gennarini, MD 
Cabozantinib-S-Malate in Treating Patients With Advanced Solid Tumors and Human Immunodeficiency Virus Solid Tumor,HIV/AIDS,Infectious Diseases,Oncology (Medical/Hematologic),Sexually Transmitted Diseases (STD),Neoplasms  Lakshmi Rajdev, MD 
Chemotherapy Before Surgery and Tissue Sample Collection in Patients With Stage IIA-IIIC Breast Cancer Breast Cancer,Skin Disorders,Neoplasms  Joseph Sparano, MD 
Collecting and Studying Tissue Samples From Patients With HIV-Associated Malignancies Gastrointestinal Cancer,HIV/AIDS,Anal Cancer,Cancer and Genetics,Gastroenterology & Liver Diseases,Oncology (Medical/Hematologic),Urologic Oncology (Med Onc),Lymphatic and Spleen Diseases,Lymphoproliferative Disorders,Urogenital Neoplasms,Immune System Diseases  Joseph Sparano, MD 
Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations Blood and Bone Marrow Cancer,Pediatric Hematology/Oncology,Leukemia,Lymphoma,Lymphatic and Spleen Diseases,Neoplasms,Lymphoproliferative Disorders,Immune System Diseases  Lisa Gennarini, MD 
Combination Chemotherapy, Gemcitabine Hydrochloride, and Radiation Therapy Before Surgery in Treating Patients With Borderline Resectable Pancreatic Cancer Gastrointestinal Cancer,Pancreatic Cancer,Gastroenterology & Liver Diseases,Oncology (Medical/Hematologic),Carcinoma,Neoplasms  Lakshmi Rajdev, MD 
Comparison of Operative to Monitoring and Endocrine Therapy (COMET) Trial For Low Risk DCIS: A Phase III Prospective Randomized Trial Breast Cancer,Family and Social Medicine,Oncology (Medical/Hematologic),Carcinoma,Neoplasms  Sheldon Feldman, MD 
Crizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Removed by Surgery and ALK Fusion Mutations (An ALCHEMIST Treatment Trial) Lung Cancer,Solid Tumor,Lung Diseases,Carcinoma,Neoplasms  Haiying Cheng, MD 
Determining Change in Cardiovascular and Metabolic Risks in Patients With Chronic Phase Chronic Myeloid Leukemia Receiving BCR-ABL Tyrosine Kinase Inhibitor First-Line Therapy in the United States Blood and Bone Marrow Cancer,Hematologic Diseases,Oncology (Medical/Hematologic),Leukemia,Neoplasms  Olga Derman, MD 
Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer Breast Cancer,Women`s Health,Skin Disorders,Carcinoma,Neoplasms  Della Makower, MD 
Efficacy and Safety of Pembrolizumab (MK-3475) With Platinum Doublet Chemotherapy as Neoadjuvant/Adjuvant Therapy for Participants With Resectable Stage IIB or IIIA Non-small Cell Lung Cancer (MK-3475-671/KEYNOTE-671) Lung Cancer,Oncology (Medical/Hematologic),Lung Diseases,Carcinoma,Neoplasms  Balazs Halmos, MD 
Elacestrant Monotherapy vs. Standard of Care for the Treatment of Patients With ER+/HER2- Advanced Breast Cancer Following CDK4/6 Inhibitor Therapy: A Phase 3 Randomized, Open-label, Active-controlled, Multicenter Trial Breast Cancer,Skin Disorders,Oncology (Medical/Hematologic),Neoplasms  Joseph Sparano, MD 
Erlotinib Hydrochloride in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Completely Removed by Surgery (An ALCHEMIST Treatment Trial) Lung Cancer,Lung Diseases,Carcinoma,Neoplasms  Haiying Cheng, MD 
Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3) Gynecologic Oncology,Obstetrics & Gynecology and Women`s Health,Human Papilloma Virus (HPV),Carcinoma,Urogenital Neoplasms  Anne Van Arsdale, MD 
Everolimus in Patients With Pancreatic Neuroendocrine Tumors Metastatic to the Liver Previously Treated With Surgery Pancreatic Cancer  Steven Libutti, MD  
Exemestane With or Without Entinostat in Treating Postmenopausal Patients With Recurrent Hormone Receptor-Positive Breast Cancer That Is Locally Advanced or Metastatic Breast Cancer  Della Makower, MD  
Exploratory Study Of The ERCC-1 Gene Expression In Colorectal Cancer Cell Lines And In Patients With Colorectal Cancer Colon, Colorectal and Rectal Cancer  Sanjay Goel, MD 
FLT3 Ligand Immunotherapy and Stereotactic Radiotherapy for Advanced Non-small Cell Lung Cancer (FLT3) Lung Cancer  Nitin Ohri, MD 
Fulvestrant and/or Anastrozole in Treating Postmenopausal Patients With Stage II-III Breast Cancer Undergoing Surgery Breast Cancer  Della Makower, MD  
Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial) Lung Cancer,Cancer and Genetics  Steven Keller, MD 
Implementation of a Prospective Financial Impact Assessment Tool in Patients With Metastatic Colorectal Cancer Colon, Colorectal and Rectal Cancer,Gastrointestinal Cancer,Gastroenterology & Liver Diseases,Oncology (Medical/Hematologic),Neoplasms  Sanjay Goel, MD 
Insights Into Microbiome and Environmental Contributions to Sickle Cell Disease and Leg Ulcers Study (INSIGHTS Study) Blood Disorders and Diseases  Caterina Minniti, MD 
Lung-MAP: Biomarker-Targeted Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer Lung Cancer  Haiying Cheng, MD 
Maintenance Systemic Therapy Versus Local Consolidative Therapy (LCT) Plus Maintenance Systemic Therapy for Limited Metastatic Non-Small Cell Lung Cancer (NSCLC): A Randomized Phase II/III Trial Lung Cancer,Radiation Oncology,Lung Diseases,Carcinoma,Neoplasms  Nitin Ohri, MD 
MarginProbe® System U.S. Post-Approval Study Protocol CP-07-001 Breast Cancer,Women`s Health,Surgery,Family and Social Medicine,Carcinoma  Sheldon Feldman, MD 
Matched Targeted Therapy (MTT) Recommendation for Patients with Recurrent, Refractory, or High Risk Leukemias Blood Disorders and Diseases,Pediatric Hematology/Oncology,Leukemia,Cancer,Neoplasms  Lisa Gennarini, MD 
Memantine Hydrochloride and Whole-Brain Radiotherapy With or Without Hippocampal Avoidance in Reducing Neurocognitive Decline in Patients With Brain Metastases Brain Cancer,Metastatic Cancer  William Bodner, MD 
Molecular and Genomic Profiling of Head and Neck Tumors Lung Cancer,Cancer and Genetics  Richard Smith, MD 
Monitoring Neoadjuvant Chemotherapy Response In Breast Cancer Patients Using Diffuse Optical Spectroscopic Imaging (DOSI) Breast Cancer,Bones, Muscles & Joints (Orthopaedics),Orthopedic Surgery - Cancer,Neoplasms  Bang Hoang, MD 
Multicenter Cohort Study To Evaluate Outcomes After Receipt of Targeted Therapy Matched to an Individualized Cancer Therapy (iCat) Recommendations in Children and Young Adults With Solid Tumors: The iCat2, GAIN Consortium Study Solid Tumor,Hematologic Diseases,Pediatric Hematology/Oncology,Cancer  Daniel Weiser, MD 
Multicenter, Open Label, Phase 3 Study of Tabelecleucel for Solid Organ Transplant Subjects With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure of Rituximab or Rituximab and Chemotherapy (ALLELE) Pediatric Hematology/Oncology,Pediatrics,Solid Organ Transplant (SOT) Complications,Epstein-Barr Virus (EBV),Lymphoproliferative Disorders,Immune System Diseases  David Loeb, MD 
Multicenter, Open Label, Phase 3 Study of Tabelecleucel for Solid Organ Transplant Subjects With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure of Rituximab or Rituximab and Chemotherapy (ALLELE) Medical and Hematologic Oncology,Solid Organ Transplant (SOT) Complications,Epstein-Barr Virus (EBV),Lymphoproliferative Disorders,Immune System Diseases  Ioannis Mantzaris, MD 
Multicenter, Open-label, Clinical and Pharmacokinetic Study of PM060184 in Combination With Gemcitabine in Selected Patients With Advanced Solid Tumors Solid Tumor  Sanjay Goel, MD 
Multicenter, Open-Label, Phase 3 Study of Tabelecleucel for Allogeneic Hematopoietic Cell Transplant Subjects With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure of Rituximab (MATCH Study) Pediatric Hematology/Oncology,Cancer,Lymphoma,Lymphatic and Spleen Diseases,Epstein-Barr Virus (EBV),Lymphoproliferative Disorders,Immune System Diseases  David Loeb, MD 
NCI-MATCH: Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors or Lymphomas Solid Tumor,Blood and Bone Marrow Cancer  Balazs Halmos, MD 
Nivolumab After Surgery and Chemotherapy in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer (An ALCHEMIST Treatment Trial) (ANVIL) Lung Cancer,Medical and Hematologic Oncology,Lung Diseases,Carcinoma,Neoplasms  Haiying Cheng, MD 
Nivolumab and Ipilimumab in Treating Patients With Advanced HIV Associated Solid Tumors Solid Tumor,HIV/AIDS  Lakshmi Rajdev, MD 
NRG-GI002 A Phase II Clinical Trial Platform of Sensitization Utilizing Total Neoadjuvant Therapy (TNT) in Rectal Cancer Radiation Oncology  Rafi Kabarriti, MD 
Observational Cohort Study of Patients With Castration-Resistant Prostate Cancer (CRPC) (TRUMPET) Prostate Cancer  Benjamin Gartrell, MD  
Olaparib as Adjuvant Treatment in Patients With Germline BRCA Mutated High Risk HER2 Negative Primary Breast Cancer (OlympiA) Breast Cancer  Jesus Anampa Mesias, MD  
Open-label, Phase I/II Study to Evaluate Pharmacokinetics, Pharmacodynamics, Safety, and Anticancer Activity of Avelumab in Pediatric Subjects From Birth to Less Than 18 Years of Age With Refractory or Relapsed Solid Tumors and Lymphoma Solid Tumor,Pediatric Hematology/Oncology,Lymphoma,Lymphatic and Spleen Diseases,Neoplasms,Lymphoproliferative Disorders,Immune System Diseases  David Loeb, MD 
Patient-Derived Models Tissue Procurement Protocol for the National Cancer Institute (NCI) Oncology (Medical/Hematologic),Cancer,Neoplasms  Joseph Sparano, MD 
Patient-Reported Outcomes Following Chemoradiotherapy for Locally Advanced Non-small Cell Lung Cancer: A Randomized Trial Comparing Two Radiotherapy Schedules Lung Cancer,Radiation Oncology,Lung Diseases,Carcinoma,Neoplasms  Nitin Ohri, MD 
Pazopanib Hydrochloride in Treating Patients With Metastatic Kidney Cancer Who Have No Evidence of Disease After Surgery Kidney Cancer  Benjamin Gartrell, MD  
Phase 1/2 Study of Vactosertib (TEW-7197) Monotherapy in Patients With Low or Intermediate Myelodysplastic Syndromes Blood and Bone Marrow Cancer,Myelodysplastic Syndrome (MDS),Hematologic Diseases,Oncology (Medical/Hematologic),Cancer,Neoplasms  Amit Verma, MD 
Phase 1/2, First-in-Human, Dose-Escalation Study of X-396 in Patients With Advanced Solid Tumors and Expansion Phase in Patients With ALK-positive Non-Small Cell Lung Cancer Lung Cancer,Solid Tumor  Haiying Cheng, MD 
Phase 1/2, Multicenter, Open-label, Multiple-Dose First-in-human Study of U3-1402, in Subjects With HER3 Positive Metastatic Breast Cancer Breast Cancer,Skin Disorders,Metastatic Cancer,Oncology (Medical/Hematologic),Neoplasms  Sun Young Oh, MD 
Phase 2 Multi-center Study of Pembrolizumab in Combination With Platinum-based Doublet Chemotherapy in Patients With EGFR Mutation and ALK Positive NSCLC (Non-Small Cell Lung Cancer) w/Progressive Disease Following Prior Tyrosine Kinase Inhibitors (TKIs) Lung Cancer,Lung Diseases,Carcinoma,Neoplasms  Balazs Halmos, MD 
Phase 2 Trial of Lenvatinib (E7080) in Subjects With Iodine-131 Refractory Differentiated Thyroid Cancer to Evaluate Whether an Oral Starting Dose of 20 mg or 14 mg Daily Will Provide Comparable Efficacy to a 24 mg Starting Dose, But Have a Better Safety Thyroid Cancer  Missak Haigentz, MD 
Phase 2a Study of BAX69 and 5-FU/Leucovorin or Panitumumab Versus Standard of Care in Subjects With Metastatic Colorectal Cancer Colon, Colorectal and Rectal Cancer  Sanjay Goel, MD 
Phase I and Dose-Expansion Study of Ibrutinib and R-da-EPOCH for Front Line Treatment of AIDS-Related Lymphomas HIV/AIDS,Oncology (Medical/Hematologic),Lymphoma,Sexually Transmitted Diseases (STD),Lymphatic and Spleen Diseases,Neoplasms  Ioannis Mantzaris, MD 
Phase I TITE-CREM Dose Escalation Study of Fractionated Stereotactic Radiation Therapy (FSRT) in Unresected Brain Metastases Brain and Neurological,Brain Cancer,Radiation Oncology,Neoplasms,Nervous System Diseases  Madhur Garg, MD 
Phase I/II Trial of Ruxolitinib in Combination With Trastuzumab in Metastatic HER2 Positive Breast Cancer Breast Cancer  Della Makower, MD  
Phase Ib Feasibility Trial of Neoadjuvant Nivolumab/Lirilumab in Cisplatin-Ineligible Muscle-Invasive Bladder Cancer Bladder Cancer,Oncology (Medical/Hematologic),Urologic Oncology (Med Onc),Urologic Diseases,Neoplasms  Benjamin Gartrell, MD 
Phase Ib/II Study of Concurrent Durvalumab And Radiation Therapy (DUART) Followed by Adjuvant Durvalumab in Patients With Urothelial Cancer (T2-4 N0-2 M0) of the Bladder: Big Ten Cancer Research Consortium BTCRC-GU15-023 Bladder Cancer,Urologic Oncology (Med Onc),Urologic Diseases,Neoplasms  Alexander I. Sankin, MD 
Phase II Randomized Trial of Radiotherapy With or Without Cisplatin for Surgically Resected Squamous Cell Carcinoma of the Head and Neck (SCCHN) With TP53 Sequencing Head and Neck Cancer,Oncology (Medical/Hematologic),Carcinoma,Neoplasms  Balazs Halmos, MD 
Phase II Study of Lenalidomide and Eltrombopag in Patients with Symptomatic Anemia in Low or Intermediate I Myelodysplastic Syndrome Blood and Bone Marrow Cancer,Myelodysplastic Syndrome (MDS)  Amit Verma, MD 
Phase II Trial of Pembrolizumab (MK-3475) in Subjects with Metastatic Castration-Resistant Prostate Cancer (mCRPC)(KEYNOTE-199) Prostate Cancer,Medical and Hematologic Oncology,Neoplasms  Benjamin Gartrell, MD 
Phase II Trial Testing the Antiemetic Efficacy of a Single-day Low Dose Aprepitant (or Fosaprepitant) Added to a 5-HT3 Receptor Antagonist Plus Dexamethasone in Patients Receiving Carboplatin Oncology (Medical/Hematologic),Cancer  Richard Gralla, MD 
Phase III Randomized Adjuvant Study of MK-3475 (Pembrolizumab) in Muscle Invasive and Locally Advanced Urothelial Carcinoma (AMBASSADOR) Versus Observation Bladder Cancer,Oncology (Medical/Hematologic),Carcinoma,Neoplasms  Benjamin Gartrell, MD 
Pilot Study Assessing the Effect of Cyclin-dependent Kinase 4/6 Inhibitors on Body Composition in Patients With ER+/HER2- Metastatic Breast Cancer Breast Cancer,Skin Disorders,Oncology (Medical/Hematologic),Neoplasms  Jesus Anampa Mesias, MD 
Pilot Study of Adoptive Cell Transfer for the Treatment of Metastatic Cancer that Expresses NY-ESO-1 Using Lymphodepleting Conditioning Followed by Infusion of Anti-NY ESO-1 Murine TCR-Gene Engineered Lymphocytes Brain Cancer,Metastatic Cancer,Medical and Hematologic Oncology,Oncology (Medical/Hematologic),Neoplasms  Ira Braunschweig, MD 
Platinum Based Chemotherapy or Observation in Treating Patients With Residual Triple-Negative Basal-Like Breast Cancer Following Neoadjuvant Chemotherapy Breast Cancer  Joseph Sparano, MD 
Pregnancy Outcome and Safety of Interrupting Therapy for Women With Endocrine Responsive Breast Cancer (POSITIVE) Breast Cancer  Joseph Sparano, MD 
Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY): A Multi-Center International Randomized Controlled Trial Comparing Alternative Antibiotic Regimens in Patients Undergoing Tumor Resections With Endoprosthetic Replacements Bone Cancer,Surgery,Infectious Diseases,Cancer,Musculoskeletal Diseases,Neoplasms  David Geller, MD 
PROSPECT: Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer Undergoing Surgery Colon, Colorectal and Rectal Cancer  Rebecca Levine, MD  
Protocol For A Research Database For Hematopoietic Stem Cell Transplantation, Other Cellular Therapies and Marrow Toxic Injuries Blood and Bone Marrow Cancer,Blood Disorders and Diseases,Hematologic Diseases,Oncology (Medical/Hematologic),Pediatric Hematology/Oncology,Neoplasms  Ira Braunschweig, MD 
Protocol for a Research Sample Repository for Allogeneic Hematopoietic Stem Cell Transplantation Blood and Bone Marrow Cancer,Blood Disorders and Diseases,Autoimmune Diseases  Ira Braunschweig, MD 
Radiation Therapy Sandwiched Between Paclitaxel and Carboplatin in Patients With High-risk Endometrial Cancer Gynecologic Cancer  Dennis Kuo, MD 
Randomized Phase II/III Study of Combination of Cediranib and Olaparib Compared to Cediranib or Olaparib Alone, or Standard of Care Chemotherapy in Women w/Recurrent Platinum-Resistant or -Refractory Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Gynecologic Cancer,Gynecologic Oncology,Obstetrics & Gynecology and Women`s Health,Carcinoma,Urogenital Neoplasms  Nicole Nevadunsky, MD 
Randomized Study of Erlotinib vs Observation in Patients With Completely Resected Epidermal Growth Factor Receptor (EGFR) Mutant Non-Small Cell Lung Cancer (NSCLC) (An ALCHEMIST Treatment Trial) Lung Cancer,Medical and Hematologic Oncology,Lung Diseases,Carcinoma,Neoplasms  Haiying Cheng, MD 
Rebastinib Plus Antitubulin Therapy With Paclitaxel or Eribulin in Metastatic Breast Cancer Breast Cancer  Jesus Anampa Mesias, MD 
Registry of Guardant360® Use and Outcomes In People With Advanced Cancer Lung Cancer,Lung Diseases,Carcinoma  Balazs Halmos, MD 
Reproductive Health Program in Patients With Cancer Supportive Cancer Care  Della Makower, MD  
Risk-Stratified Randomized Phase III Testing of Blinatumomab (NSC#765986) in First Relapse of Childhood B-Lymphoblastic Leukemia (B-ALL) Oncology (Medical/Hematologic),Leukemia,Non-Hodgkins Lymphoma,Lymphoma,Neoplasms,Epstein-Barr Virus (EBV),Lymphoproliferative Disorders  Lisa Gennarini, MD 
RT CHARM: Phase III Randomized Trial of Hypofractionated Post Mastectomy Radiation With Breast Reconstruction Breast Cancer,Women`s Health,Radiation Oncology,Carcinoma,Neoplasms  Jana Fox, MD 
S1207 Hormone Therapy With or Without Everolimus in Treating Patients With Breast Cancer (e3) Breast Cancer  Della Makower, MD  
S1314, A Randomized Phase II Study of Co-Expression Extrapolation (COXEN) With Neoadjuvant Chemotherapy for Localized, Muscle-Invasive Bladder Cancer Medical and Hematologic Oncology  Benjamin Gartrell, MD 
S1314, Co-expression Extrapolation (COXEN) Program to Predict Chemotherapy Response in Patients With Bladder Cancer (COXEN) Bladder Cancer  Benjamin Gartrell, MD  
S1505: Combination Chemotherapy or Gemcitabine Hydrochloride and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Before Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery Pancreatic Cancer  Lakshmi Rajdev, MD 
Safety and Efficacy of RRx-001 in the Attenuation of Oral Mucositis in Patients Receiving Chemoradiation for the Treatment of Oral Cancers Gastrointestinal Cancer,Head and Neck Cancer,Oncology (Medical/Hematologic),Radiation Oncology,Oral Mucositis  Rafi Kabarriti, MD 
Safety and Pharmacokinetics of Atezolizumab Combination Treatments in Participants With HER2-Positive and HER2-Negative Breast Cancer Medical and Hematologic Oncology  Sun Young Oh, MD 
Safety Study of ALRN-6924 in Patients With Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome Blood and Bone Marrow Cancer,Myelodysplastic Syndrome (MDS)  Amit Verma, MD 
Single Arm Study Treating Patients of Peritoneal Surface Malignancy (Colorectal, Appendical, Pseudomyxoma, Gastric) With Cytoreductive Surgery and Hyperthermic Intraperitoneal Mitomycin-C Gastrointestinal Cancer  Haejin In, MD 
Sorafenib Tosylate With or Without Stereotactic Body Radiation Therapy in Treating Patients With Liver Cancer Liver Cancer  Nitin Ohri, MD 
Standard or Comprehensive Radiation Therapy in Treating Patients With Early-Stage Breast Cancer Previously Treated With Chemotherapy and Surgery Breast Cancer  Jana Fox, MD 
Study of Efficacy of Ribociclib After Progression on CDK4/6 Inhibition in Patients With HR+ HER2- Advanced Breast Cancer (MAINTAIN) Breast Cancer,Women`s Health,Oncology (Medical/Hematologic),Carcinoma,Neoplasms  Sun Young Oh, MD 
Study of Voicing My CHOiCES as a Tool for Advanced Care Planning in Young Adults With Cancer Supportive Cancer Care,Genetic Disorders,Hematologic Diseases,Cancer,Immune System Diseases  Lisa Gennarini, MD 
Study to Assess Safety and Efficacy of Atezolizumab (MPDL3280A) Compared to Best Supportive Care Following Chemotherapy in Patients With Lung Cancer [IMpower010] Lung Cancer  Steven Keller, MD 
Study To Compare Avelumab In Combination With Standard of Care Chemoradiotherapy (SoC CRT) Versus SoC CRT for Definitive Treatment In Patients With Locally Advanced Squamous Cell Carcinoma Of The Head And Neck (JAVELIN HEAD AND NECK 100) Medical and Hematologic Oncology  Balazs Halmos, MD 
TAILOR RT: A Randomized Trial of Regional Radiotherapy in Biomarker Low Risk Node Positive Breast Cancer Breast Cancer,Neoplasms  Jana Fox, MD 
Targeted Intra-arterial Gemcitabine vs. Continuation of IV Gemcitabine Plus Nab-Paclitaxel Following Induction With Sequential IV Gemcitabine Plus Nab-Paclitaxel and Radiotherapy for Locally Advanced Pancreatic Cancer (TIGeR-PaC) Pancreatic Cancer,Surgery,Endocrinology,Neoplasms  Peter Muscarella, MD 
Temozolomide With or Without Veliparib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme Brain Cancer  Mary Welch, MD 
Testing Decision Aids to Improve Prostate Cancer Decisions for Minority Men (Alliance A191402CD) Prostate Cancer,Urologic Oncology (Med Onc),Urologic Diseases,Cancer,Neoplasms  Evan Kovac, MD 
The Chimerix CMX001 Registry Blood and Bone Marrow Cancer  Olga Derman, MD 
The Incidence of Adjacent Synchronous Ipsilateral Infiltrating Carcinoma and/or DCIS in Patients Diagnosed With Intraductal Papilloma Without Atypia or Flat Epithelial Atypia by Core Needle Biopsy Cancer,Carcinoma,Neoplasms  Rouzan Karabakhtsian, MD 
The National Myelodysplastic Syndromes Natural History Study Blood Disorders and Diseases,Myelodysplastic Syndrome (MDS),Hematologic Diseases,Medical and Hematologic Oncology,Oncology (Medical/Hematologic),Cancer,Neoplasms  Aditi Shastri, MD 
The Selective Personalized Radio-Immunotherapy for Locally Advanced NSCLC Trial (SPRINT) Lung Cancer,Neurology,Radiation Oncology,Carcinoma,Neoplasms  Nitin Ohri, MD 
Therasphere for Unresectable Primary or Secondary Liver Neoplasia Oncology (Medical/Hematologic)  Renee Moadel, MD 
TMEM-MRI: A Pilot Feasibility Study of Magnetic Resonance Imaging for Imaging of TMEM (Tumor Microenvironment of Metastasis) in Patients With Operable Breast Cancer Breast Cancer,Skin Disorders,Neoplasms  Jesus Anampa Mesias, MD 
Tomosynthesis Mammographic Imaging Screening Trial (TMIST) Breast Cancer,Women`s Health,Oncology (Medical/Hematologic),Radiation Oncology  Beatriu Reig, MD 
Topical or Ablative Treatment in Preventing Anal Cancer in Patients With HIV and Anal High-Grade Squamous Intraepithelial Lesions (ANCHOR) HIV/AIDS,Anal Cancer  Rebecca Levine, MD 
Transoral Surgery Followed By Low-Dose or Standard-Dose Radiation Therapy With or Without Chemotherapy in Treating Patients With HPV Positive Stage III-IVA Oropharyngeal Cancer Head and Neck Cancer  Missak Haigentz, MD 
Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Children and Adolescents Pediatric Hematology/Oncology,Leukemia,Lymphatic and Spleen Diseases,Neoplasms,Lymphoproliferative Disorders  Lisa Gennarini, MD 
Veliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney Dysfunction Solid Tumor  Sanjay Goel, MD 
Whole-Brain Radiation Therapy With or Without Hippocampal Avoidance in Treating Patients With Limited Stage or Extensive Stage Small Cell Lung Cancer Lung Cancer  William Bodner, MD