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Current Clinical Trials

Clinical Trial for a New Acute Treatment for Migraine

We are seeking patients with 1 to 8 days of migraine headaches per month and who currently treat their migraines with Fioricet® and/or other butalbital-containing combination medications (BCM) to participate in a research study evaluating TreximaTM, a new investigational medication for the acute treatment of migraine. BCMs and other barbiturates are among the most commonly prescribed medications for the treatment of migraine headaches; however, they are often associated with many serious and undesirable side effects. Participants in this study will be asked to treat 3 separate migraine attacks within a 19 week period with one of three study medications: TreximaTM, a BCM, or placebo. Qualified participants will receive all study-related care at no charge. Reimbursement for time and travel may also be available.

For more information, please contact our research coordinators at (718) 405-8007. Principal Investigator: Brian Grosberg, MD; IRB#: 07-02-268-01; IRB approved through 2/13/2009.

 

Clinical Trial for a New Preventive Treatment for Migraine

We are seeking patients with 3 to 12 days of migraine headaches per month to participate in a research study to test the effectiveness of Tonabersat (SB-220453), the first drug specifically designed to prevent migraine headaches. Currently, all of the medications used for the prevention of migraine were developed to treat other conditions such as high blood pressure, epilepsy or depression. In order to properly measure the effects of Tonabersat, patients will be randomly assigned to one of three treatment groups. This study will be conducted over 20 weeks with up to 7 clinic visits. At the end of the study it will be possible for patients to enter a longer study in which all patients will receive Tonabersat. Qualified participants will receive all study-related care at no charge. Reimbursement for time and travel may also be available.

For more information, please contact our research coordinators at (718) 405-8007. Principal Investigator: Brian Grosberg, MD; IRB#: 07-02-140-01; IRB approved through 7/4/2008.

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Marianne O'Hara, C.P.N.P.

Nurse Practitioner, Department of Urology
Children's Hospital at Montefiore - CHAM


People want to work here, they want to be part of this extraordinary hospital for children. [more]


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