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Title   A Study of the Safety and Efficacy of ONO-7746 in Adult Cancer Patients With Chemotherapy Induced Thrombocytopenia
Description   The primary purpose of this study is to evaluate the safety and tolerability of ONO-7746 across multiple doses in patients with solid tumors and chemotherapy induced thrombocytopenia (CIT) scheduled to receive at least two cycles of myelosuppressive chemotherapy on Day 1 every 21 days at the same dosages and schedule in the study.

The secondary objectives are to characterize the PK profiles of ONO-7746 and to explore the pharmacodynamic effect of ONO-7746 on CIT.

Eligibility Criteria   To be eligible for this study, patients must meet several criteria, including but not limited to the following:

* Patient must be 18 Years and older

* Subject must have experienced thrombocytopenia as evidenced by a platelet count less than 100 Gi/L in the preceding cycle immediately before study enrollment.
Principal Investigator   Sanjay Goel, MD
Phone   (718) 904-2488
Contact Email   sgoel@montefiore.org
Post Date   04/21/2011
Protocol Number   11-05-188/West
Status   Recruiting
Current Trial Type   Interventional
Adult Clinical Trial   No
Pediatric Clinical Trial   No