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Title   Chemotherapy and Pelvic Radiation Therapy With or Without Additional Chemotherapy in Treating Patients With High-Risk Early-Stage Cervical Cancer After Radical Hysterectomy
Disease/Condition   Cervical Cancer
Description   The purpose of this trial is to study chemotherapy and pelvic radiation therapy to see how well they work when given with or without additional chemotherapy in treating patients with high-risk early-stage cervical cancer after radical hysterectomy.

Drugs used in chemotherapy, such as cisplatin, paclitaxel, and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.

Radiation therapy uses high-energy x-rays to kill tumor cells. It is not yet known whether chemotherapy and radiation therapy are more effective when given with or without additional chemotherapy in treating cervical cancer.
Eligibility Criteria   To be eligible for this study, patients must meet several criteria, including but not limited to the following:

* Patient must be 18 Years and older

* Patient must have histologically confirmed squamous, adenosquamous, or adenocarcinoma of the cervix with any/all high-risk after surgery.

* Patient must have undergone radical hysterectomy (open, laparoscopically, or robotic) and staging within the past 70 days.

Principal Investigator   Mark Einstein, MD
Contact Name   Loraine Centrilla, RN
Phone   (718) 405-8200
Contact Email   lcentril@montefiore .org
Post Date   09/18/2009
Protocol Number   10-04-095/West
Status   Recruiting
Current Trial Type   Interventional
Adult Clinical Trial   No
Pediatric Clinical Trial   No