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Title   Pharmacokinetics and Safety Study of Azacitidine in Cancer Patients With and Without Impaired Renal Function (RENAL)
Description   The purpose of this study is to evaluate the following:

* Whether azacitidine is absorbed in the body at the same rate or proportion for different concentrations.

* Determine the effect renal impairment has or does not have on the absorption of azacitidine.

* Determine if azacitidine is safe and well tolerated in patients with renal function impairment.

Eligibility Criteria   To be eligible for this study, patients must meet several criteria, including but not limited to the following:

* Patient must be 18 years and older

* MDS according to the FAB classification system (RA, RARS, RAEB, RAEB-T, CMML), AML in remission, malignant solid tumor, MM, NHL, or HD.

* Patient must have a life expectancy more than or equal to 3 months

* Patient must be a nonsmoker or must not have smoked for at least 30 days before the screening visit and agree to abstain from smoking during study participation.
Principal Investigator   Sanjay Goel, MD
Phone   (718) 904-2488
Contact Email   sgoel@montefiore.org
Post Date   04/01/2008
Protocol Number   10-09-298/West
Status   Recruiting
Current Trial Type   Interventional
Montefiore Clinical Trial   No
CHAM Clinical Trial   No