Montefiore - Einstein Heart Center

David A. D'Alessandro, MD

Montefiore-Einstein Medical Center
3400 Bainbridge Avenue
Bronx, New York 10467
Phone: 718-920-6515
ddalessa@montefiore.org

Positions and Appointments

  Jan. 2005-July 2005   Instructor in Clinical Surgery
Department of Surgery, Division of Cardiothoracic Surgery
College of Physicians and Surgeons of Columbia University, New York, N.Y.
       
  July 2005–Present   Assistant Professor of Cardiovascular and Thoracic Surgery
Albert Einstein College of Medicine, Bronx, N.Y.
       
  Jan.-July 2005   Assistant Attending Surgeon
Department of Surgery, Division of Cardiothoracic Surgery
New York Presbyterian Hospital/Columbia University Medical Center, New York, N.Y.
       
  July 2005-Present   Attending Surgeon
Department of Cardiovascular and Thoracic Surgery
Montefiore Medical Center, Bronx, NY

 

Education and Training

 

  1991   Cornell University
School of Agriculture and Life Sciences
Bachelor of Science
       
  1992   Columbia University
School of General Studies
Post baccalaureate Premedical Program
       
  1993-1997   MD
Columbia University College of Physicians & Surgeons
Alpha Omega Alpha

Dean’s Summer Research Fellowship
Robert G. Bertsch Prize
       
  June 1997-June 2000   Resident, General Surgery
New York Presbyterian Hospital/Columbia University Medical Center, New York, N.Y.
       
  July 2000-May 2001   Research Fellow, Cardiothoracic Surgery
College of Physicians & Surgeons of Columbia University, New York, N.Y.
       
  June 2001-June 2002   Resident, General Surgery
New York Presbyterian Hospital/Columbia University Medical Center, New York, N.Y.
       
  July 2002-Dec. 2002   Fellowship, Renal Transplant
New York Presbyterian Hospital/Columbia University Medical Center, New York, N.Y.
       
  Jan. 2003-Dec. 2004   Resident, Thoracic Surgery
New York Presbyterian Hospital/Columbia University Medical Center, New York, N.Y.

 

Research

  1994   Department of Surgery, Dr. Mehmet Oz.
- Ventricular performance in an isolated human heart model.
- Effects of vasopressin in vasodilatory shock.
- Development of percutaneous implantable device for treatment of aortic insufficiency.
- Use of venoarterial shunting for treatment of right heart failure.
       
  1995   Department of Surgery, Dr. Henry Spotnitz.
- Validation study of vascular flow probes in porcine model.

 

Honors and Awards

  Columbia University College of Physicians & Surgeons
Dean's Summer Research Fellowship
Robert G. Bertsch Prize
Alpha Omega Alpha
   
 
Best Doctors, Inc.
"The Best Doctors in America"
2009-2010

 

Board Certifications

American Board of Surgery, 2004

American Board of Thoracic Surgery, 2006


Patents

U.S. Patent No. 6,767,324
Epicardial cooled stabilizer for beating heart surgery
Issued July 27, 2004


Publications

Journals

  1. Stern DR, Kazam J, Edwards P, Maybaum S, Bello RA, D'Alessandro DA, Goldstein DJ. Increased incidence of gastrointestinal bleeding following implantation of the HeartMate II LVAD. J Card Surg (Online/ In Press). 
  2. Ryan S, Chirumamilla V, Bello RA, D'Alessandro DA, Michler RE, Rabin J, Ashton RC, DeRose JJ.  How Informed is "Informed consent" for robotic cardiothoracic surgery? Innovations 2009;4(6):307-10. 
  3. D'Alessandro DA, Kajstura J, Hosoda T, Zheng H, Bello R, Gatti A, Padin-Iruegas ME, Carvalho AB,  Mosna F, Bardelli S, Bearzi C, Rota M, Zembala MO, Stern D, Rimoldi O, Urbanek K, Michler RE, Leri A, Anversa P. Progenitor cells from the recipient generate immunocompatible myocardium within the transplanted heart. Circulation Research 2009;105(11):1128-40. 
  4. Stern DR,  Steiner C, Bello RA, Sutton N, Spevack DM, Galina L, Michler RE, D'Alessandro DA, Weinstein S. Congenitally corrected transposition of the great arteries and concomitant coronary artery and valvular disease in the adult patient. Congenital Heart Disease. (Accepted for Publication) 
  5. Bearzi C, Leri A, Monaco FL, Rota M, Gonzalez A, Hosoda T,  Pepe M, Qanud K, Ojaimi C, Bardelli S, D'Amario D, D'Alessandro DA,  Michler RE, Dimmeler S, Zeiher AM, Urbanek K, Hintze TH, Kajstura J, Anversa P. Identification of a coronary vascular progenitor cell in the human heart.  Proceedings of the National Academy of Sciences of the United States of America 2009;106 (37):15885-90. 
  6. Bearzi C, Rota M. Hosoda T, Tillmanns J, Nascimbene A, De Angelis A, Yasuzawa-Amano S, Trofimova I, Siggins RW, Lecapitaine N, Cascapera S, Beltrami AP, D'Alessandro DA, Zias E, Quaini F, Urbanek K, Michler RE, Bolli R, Kajstura J, Leri A, Anversa P. Human cardiac stem cells. Proceedings of the National Academy of Sciences of the United States of America 2007;104(35):14068-73. 
  7. Liu EH, D’Alessandro DA, Hardy MA. Ethical issues in living renal donation. Transplant Proceedings 2003;35(3):1174-6.
  8. D'Alessandro DA, Rao V, DiGiorgi PL,Oz MC. Current options for mechanical heart technology. Journal of Cardiac Surgery 2002;17(1): 81-8.
  9. Landry DW, Levin HR, Gallant EM, Seo S, D'Alessandro DA, Oz MC, Oliver JA. Vasopressin pressor hypersensitivity in vasodilatory septic shock. Critical Care Medicine 1997;25(8):1279-82.
  10. Landry DW, Levin HR, Gallant EM, Ashton RC Jr, Seo S, D'Alessandro D, Oz MC, Oliver JA. Vasopressin deficiency contributes to the vasodilitation of septic shock. Circulation 1997;95(5):1122-5.
  11. Goldstein DJ, Ashton RC, Slater JP, Pearson M, Seldomridge JA, D'Alessandro DA, Jordan DA, Oz MC. Venoarterial shunting for the treatment of right sided circulatory failure following left ventricular assist device placement. ASAIO 1997;43(3):171-6.
  12. Dean DA, Cabreriza SE, Jia C-X, D'Alessandro DA, Sardo MJ, Chalik N, Soto PF, Dickstein ML, Spotnitz HM. Validation study of a new transit-time ultrasonic flow probe for continuous measurements of the great vessels. ASAIO 1996;42(5):M671-6
  13. Ashton RC, Jr., Goldstein DJ, D'Alessandro D, Weinberg AD, Burkhoff D, Rosskothen HD, Lemole GM, Oz MC. Development of an intraluminal device for the treatment of aortic regurgitation: prototype and in vitro testing system. Journal of Thoracic and Cardiovascular Surgery1996;112(4):979-983.
  14. Gandsas A, Sadeghi A, Mezrow CK, Midulla PS, Dapunt O, D'Alessandro D, Shiang H, Griepp RB. Pulmonary hemodynamics following reduced and single lung transplantation in a porcine model. Surgical Forum 1993;44:457-9.
  15. Mezrow CK, Midulla PS, Sadeghi A, Dapunt O, Gandsas A, Shiang H, D'Alessandro D, Griepp RB. A vulnerable interval for cerebral injury- Comparison of hypothermic circulatory arrest and low flow cardiopulmonary bypass. Cardiol Young 1993;3:287-298.

 

Abstracts and Presentations

  1. Zolty R, Vittorio T, Lowes B,  Shakar S,  Brieke A, Cannon A, Cleveland J, D'Alessandro D, Goldstein D, Maybaum S. Normalization of Fixed Pulmonary Hypertension in Severe Heart Failure Patients with Placement of Left Ventricular Assist Device. Presented at the International Society for Heart and Lung Transplantation meeting in Paris, France. April 24, 2009. 
  2. D'Alessandro DA, Bello R, Stern D, Kajstura J, Bearzi C, Goldstein D, Zembala M, Rota M, Leri A, Anversa P, Michler RE. Heart Transplantation with Adjuvant Autologous Cardiac Progenitor Cell Therapy. Presented at the International Society for Heart and Lung Transplantation meeting in Paris, France. April 23, 2009. 
  3. Bello RA, D'Alessandro DA, Maybaum S, Goldstein DJ. Predictive Factors of Early Graft Failure after Cardiac Transplantation. Presented at the International Society for Heart and Lung Transplantation meeting in Paris, France. April 23, 2009. 
  4. Stern DR, Kazam J, Shariff S, Edwards P, McAllister N, Maybaum S, Bello R, D'Alessandro D, Goldstein D.  Increased incidence of gastrointestinal bleeding following implantation of Heartmate II LVAD. Presented at the International Society for Heart and Lung Transplantation meeting in Paris, France. April 22, 2009.  
  5. D'Alessandro DA, Kajstura J, Bello R, Bearzi C, Rota M, Gatti A, D'Amario D, Mosna F, Tillmanns J, Gonzalez A, Stern D, Bardelli S,  Hosoda T, Urbanek K, Leri A, Michler RE, Anversa P. Progenitor cells from the recipient generate immunocompatible myocardium within the transplanted dog heart. Presented at American Heart Association meeting in New Orleans, LA. November 10, 2008.
  6. Cheema FH, Robin JK, Kherani AR, Greenidge EA, Rosenthal BD, Barbone A, Vigilance DW, Morgan JA, D’Alessandro DA, Morales D, Garrido M, Oliver JA, Oz MC, Landry DW. Pressor effect of vasopressin in late phase hemorrhagic shock is independent of inhibition of K+ATP channel or the nitric oxide pathway. Presented at American Heart Association meeting in Orlando, Florida. November 8, 2003.
  7. D'Alessandro DA, Barbone A, Burton EA, RaoV, et al. Venous blood cardioplegia provides superior preservation of ventricular function in ischemic myocardium. Presented at American Heart Association meeting inNew Orleans, LA. November 12, 2001.
  8. Barbone A, Holmes J, Heerdt PM, Andrew HS, D'Alessandro DA, et al. Right and left ventricular responses to LVAD support: evidence for a primary role of mechanical unloading underlying reverse remodeling (Poster). Presented at American Heart Association meeting in New Orleans, LA. November 13, 2001.
  9. Lazar RM, Heitjan DF, Kurlansky P, Leone P, D'Alessandro DA, et al. Randomized trial of on vs. off-pump CABP reveals baseline memory dysfunction. Presented at American Heart Association meeting in New Orleans, LA. November 12, 2001.
  10. Barbone, A, Reiken SR, Holmes J, D'Alessandro DA, et al. Improved adrenergic responsiveness in RV and LV following LVAD support (Poster). Presented at American Heart Association meeting in New Orleans, LA. November 13, 2001.
  11. Williams, MR, Kourpanidis S, Casher J, Barbone A, DiGiorgi PL, D'Alessandro DA, et al. epicardial atrial ablation with high intensity focused ultrasound on the beating heart (Poster). Presented at American Heart Association meeting in New Orleans, LA. November 12, 2001.
  12. D'Alessandro DA Burton EH, Danes MT, Williams MR, DiGiorgi PL, Barbone A, Oz MC. Active endocardial cooling of explanted hearts by iced saline circulated via novel intraventricular balloon catheters. Presented at New Era Cardiac Surgery meeting in Laguna Beach, CA. January 2001.
  13. D'Alessandro DA, Todd GJ, Oz MC, El-Tamer M. Breast necrosis: an unusual complication following cardiac bypass. (Poster) Presented American College of Surgeons meeting in Chicago, IL. October 2000.
  14. Dean DA, Cabreriza SE, Jia C-X, D'Alessandro DA, Sardo MJ, Chalik N, Soto PF, Dickstein ML, Spotnitz HM. Validation study of a new transit-time ultrasonic flow probe for continuous measurements of the great vessels. Presented ASAIO meeting in Washington D.C., May 1996. Published in ASAIO 1996;42(2):26.
  15. Slater JP, Lipsitz EC, Chen JM, Goldstein DJ, Ashton RC, D'Alessandro DA, Oz MC, Levin HR, Burkoff D. Ventricular interdependence in explanted human hearts. JACC Abstracts 1995;120A.
  16. Slater JP, Lipsitz EC, Chen JM, Goldstein DJ, Ashton RC, D'Alessandro DA, Oz MC, Levin HR, Burkoff D. Ventricular interdependence in explanted human hearts. JACC Abstracts 1995;120A.
  17. Dean DA, Jia C-X, Cabreriza SE, D'Alessandro DA, et al. Validation studies of transonic A- series flow probe in the aortic position using a right heart bypass model: Preliminary results. Presented at the Transonic tutorial during the Experimental Biology 95 meeting. Atlanta, GA; April 1995.
  18. Mezrow CK, Gandsas A, Midulla PS, Dapunt O, D'Alessandro DA, Shiang H, Zapulla R, Sadeghi A, Griepp RB. Cerebral function following hypothermic circulatory arrest and low flow cardiopulmonary bypass. Presented at Symposium: Neurohumoral effects of profound hypothermia in infant heart surgery. London, England; March 1993. 


Book Chapters

  1. Stern DR, D'Alessandro DA, Greenstein SM, Odim J. Heart Preservation. eMedicine from WebMD. Updated May 14, 2009. Available at: http://emedicine.medscape.com/article/1012217-overview. 
  2. Ashton A, D, D'Alessandro DA, and Michler RE. "Use of Skeletal Myoblasts for the Treatment of CongestiveHeart Failure." Contemporary Cardiology: Stem Cells and Myocardial Regeneration Ed.  M. S. Penn. Totowa, NJ: Humana Press, Inc., In Press.
  3. D’Alessandro, David A. and Michler, Robert E. “ Heart-Lung Machines.” The Wiley Encyclopedia of Medical Devices and Instramentation, Second Edition. Ed. John G. Webster. Hoboken, NJ: John Wiley & Sons, Inc., In Press.
  4. D'Alessandro, David A. and Mehmet C. Oz. "Alternative Anastomotic Techniques." Minimally Invasive Cardiac Surgery, Second Edition. Eds. Daniel J. Goldstein and Mehmet C. Oz. Totowa, NJ: Humana Press, Inc., 2004. 393-410.

 

Invited Presentations

  1. Long Term Mechanical Circulatory Support. New Frontiers in Heart Failure Management.  June 10th, 2008. Naples Italy. 
  2. Identifying Novel Mechanical Devices for Treating Heart Failure. New Frontiers in Heart Failure Management.  June 12th, 2008. Naples Italy.

 

 

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